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SAN FRANCISCO — Lebrikizumab reduced exacerbations in adolescents with uncontrolled asthma and had a favorable safety profile, according to results of the ACOUSTICS study.The study, which was stopped early by the sponsor, showed a greater treatment effect with the higher dose of lebrikizumab studied.

Suicide risk prediction in adults was optimized when utilizing both in-person screening and electronic data, according to a study published in JAMA Network Open. “Mental health diagnoses are often absent in records of those who subsequently die from suicide. Better risk identification and prognostication might improve outreach and prevention,” Drew Wilimitis, BS, of the department of

Almirall S.A. and Inserm Transfert have entered an agreement to advance research in vitiligo treatment, the two entities announced in a press release.The licensing and research collaboration agreement will focus on developing medicines that modulate the Wnt pathway.

SAN FRANCISCO — A session at the American Thoracic Society International Conference highlighted a new clinical practice guideline addressing idiopathic pulmonary fibrosis and progressive pulmonary fibrosis in adults. The new guidance comes nearly 4 years after the last guidance on the diagnosis and management of IPF, according to the ATS.

Travere Therapeutics Inc. announced the FDA has accepted and granted priority review of its new drug application under subpart H for accelerated approval of sparsentan for treatment of IgA nephropathy.According to the company press release, sparsentan is a dual endothelin angiotensin receptor antagonist that targets the endothelin A receptor and the angiotensin II subtype 1 receptor.

In a Healio interview, Douglas K. Rex, MD, president of ASGE and distinguished professor emeritus of medicine at Indiana University, details upcoming ASGE sessions that attendees should include on their agendas at Digestive Disease Week.

The CDC estimates that 107,622 overdose deaths occurred in 2021, a 14.9% increase from 2020, which previously held the record for overdose deaths in a 12-month period, according to a report from the National Center for Health Statistics. Rahul Gupta, MD, MPH, MBA, FACP, White House Office of National Drug Control Policy director, said in the report that a life is lost to overdose every 5

Implementation of an interactive training program increased clinician adherence to stroke guidelines and reduced the proportion of disabled or deceased patients with acute ischemic stroke, researchers reported in JAMA Network Open. “Although evidence-based clinical stroke guidelines provide recommendations for stroke treatments, gaps exist between the guideline recommendations and clinical

Individuals with long COVID may have a higher risk for abnormal blood clotting, especially those who have difficulties with basic exercise for more than 12 weeks after infection, according to a study published in Blood Advances. The findings highlight a potential role for antithrombotic therapy in the management of these patients, researchers noted.

Although patients with lupus nephritis may require prednisone maintenance, attempts should be made to reduce their steroid doses, said a speaker at The Future of Systemic Lupus Erythematosus Diagnosis and Treatment meeting.