Researchers at the Francis Crick Institute have found that the body’s process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or .
“By understanding more about how current antibiotics are impacted by conditions inside of cells, such as acidity, we hope it could help the search for new drugs or better drug combinations. Click to read more.
Jan 15 2021 Read 411 Times
During bacterial infections such as tuberculosis, bacteria enter human cells posing a challenge for treatment, as antibiotics must reach and enter all infected cells in order to be effective. If researchers could select for or develop more effective antibiotics based on where they reach, this may reduce the length of treatment needed, which in turn could reduce the risk of antibiotic resistance developing.
Scientists at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where in the infected tissues and in the cells, an antibiotic given to treat tuberculosis had reached the bacteria. The scientists are continuing to work on the method, adapting it for other types of antibiotic and to image multiple antibiotics at the same time.