I am karen brooks. I want to thank you both for a lifetime of science. Can you speak to the state of research and treatment for brain cancer and other such forms of cancer . We have made tremendous progress across many different fronts. Among the most challenging, to diseases i spent time studying in my laboratory is the brain cancer that took senator kennedys life and also pancreas cancer. There has been a tremendous amount of basic science work that has given us the atlas of genes in those cancers, really outstanding genetic model systems that help us understand what those genes do, but we are faced with converting noninformation into therapies that truly treat those diseases. I am cautiously optimistic of early data beginning to emerge in the immunotherapy space which may give us a foothold upon which we can build quite rapidly. A good example, another disease we studied because it is a very lent disease virulent diseases melanoma. In 2009 there were very few advances that had any i
Instead, harnesses the power of the immune system in the hopes, reawakens it so it recognizes that cancer and can attack the cancer. Those therapies are giving responses in a large fraction of patients with advanced disease. And so, if we begin to combine the targeted therapies going after the genes, harnesses the power of the immune system, i think what you will see over the next 510 years are significant reductions in cancer mortality. We are seeing cap for melanoma. And a variety of other cancers across the board. It sounds extremely complex to do targeted therapy based on specific genetic mutations. I wonder if doctors, it is one thing to be at a great institution, what if you are at some other place . Are doctors able to keep up and provide the kind of care that is made such a difference . Other great institutions, George Washington here in this area and so on and so forth, the issue is really the knowledge gap that you are referring to. It is a significant one. There was a report
That is using the polio virus to attack glioblastoma the deadliest brain cancer there is. This, to me, is the most promising therapy i have seen in my career, period. Pelley a turning point in cancer care . I hope so. I think it may well be. Pelley with that kind of promise, the scientists at duke are using the polio virus on other cancers in their labs. What have you been able to kill so far . So, we have done this for lung cancers, Breast Cancers colorectal cancers, prostate cancers, pancreatic cancers, liver cancers, renal cancers. Im steve kroft. Im lesley stahl. Im morley safer. Im bill whitaker. Im charlie rose. Im scott pelley. Those stories tonight on 60 minutes. My name is pam and this is my aha moment. My brother died from complications of obesity and diabetes. He had been overweight. It could have been prevented. And i felt that if i could change the lifestyle of one child it would make a difference. So i went in and converted a vacant classroom and turned it into a fitness
Dragging fun club because the Public Perception is that is what we are. And if i can stress one thing, and i saw mr. Samuels trying to stress it, and i would also. At one time early in my Law Enforcement career i may have had that same impression, but i have to tell you that overall i have never seen a more dedicated professional group of men and women at risk their lives and do it because they want to have a Safer Community and put themselves at great risk to do that. That aside, like any large bureaucracy envy tend to be the largest in any state or close to it, you end up with problems. It is how we react to those problems. That is why right now when i really appreciate what he have done by calling this hearing in miami participate because i can tell you that i dont know of any state in the nation that is not taking a hard look at their administrative segregation policy. You have really brought to the forefront. We all understand that as professionals the movement is this is not the
Out there is no question a great deal of progress. Adding 2. 4 million jobs marks the third Consecutive Year of job growth from february 2010 private employment has risen in 47 consecutive months for a total of 8. 5 million jobs. We think of the ups and downs with the employment data. You can see steady consistent job growth at a pace of about 190,000 private sector jobs didnt November December the resawed job growth faster than that pays. December and january it did not come up to that average for a variety of things whether the whether seasonal factors or normal boy is sid measurements that bounces around from month to month with that moving average has barely changed. With that volatility of jobs numbers is very much in line with the magnitude of that probability prior to the recession. The progress the last year was notable in part be coz of the steep decline in the federal budget deficit was the major had planned. The next figure shows the largest for your reduction of the deficit