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Tovorafenib elicited rapid, clinically meaningful tumor responses in pediatric patients with low-grade gliomas, including those with optic pathway gliomas, regardless of prior MAPK inhibitor status.

United statesBritish columbiaAlex lemonade stand foundationEducation day of the society for neuroAnnual meetingEducation dayResponse assessmentNeuro oncology high grade gliomaPediatric neuro oncology low grade gliomaGrade gliomaPatients with priorOptic pathwayPathway glioma antitumor activityDay oneLemonade stand foundationMulcahy levy