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F. Hoffmann-La Roche Ltd: Roche announces results from Evrysdi (risdiplam) study in infants with Type 1 spinal muscular atrophy (SMA) published in New England Journal of Medicine

FIREFISH Part 1 data show treatment with Evrysdi at 12 months helped 90% of these infants survive without permanent ventilation and 33% sit without support, a key motor milestone not normally seen in the
United States Nathalie Meetz Jon Kaspar Bayard Levi Garraway Daniel Grotzky Karl Mahler

F. Hoffmann-La Roche Ltd: FDA grants Breakthrough Device Designation for Roche's Elecsys Growth Differentiation Factor-15 (GDF-15) assay to help identify patients suitable for innovative treatment addressing unintentional weight loss in cancer patients

(2) FDA BDD acknowledges the importance of GDF-15 testing in identifying eligible cachexic patients with solid tumours to be treated with Pfizers investigational drug PF-06946860 Unintentional weight loss (cachexia) is a highly prevalent complication of cancer, affecting more than half of all cancer patients worldwide, potentially leading to significant functional impairment and increased risk of death Successful cachexia treatment can potentially contribute to improved cancer treatment worldwi...
United States Nathalie Meetz Jon Kaspar Bayard Daniel Grotzky Karl Mahler Sabine Borngr

FDA grants Breakthrough Device Designation for Roche's Elecsys Growth Differentiation Factor-15 (GDF-15) assay to help identify patients suitable for innovative treatment addressing unintentional weight loss in cancer patients

FDA BDD acknowledges the importance of GDF-15 testing in identifying eligible cachexic patients with solid tumours to be treated with Pfizer's...
United States Nathalie Meetz Daniel Grotzky Thomas Schinecker Patrick Barth Karsten Kleine

F. Hoffmann-La Roche Ltd: Roche reports solid results in 2020

F. Hoffmann-La Roche Ltd: Roche reports solid results in 2020 Group sales increase 1% 1 at constant exchange rates (CER); 5% decline in Swiss francs, as a result of continued appreciation of the Swiss franc against most currencies Pharmaceuticals Division sales decline 2%; continued strong sales growth of newly launched medicines (+32% 2, including Tecentriq, Hemlibra, Ocrevus, Perjeta and Kadcyla) largely offsets the impact of competition from biosimilars (CHF -5.1 billion at CER 3), but not t...
United States Nathalie Meetz Chek Sugarview Daniel Grotzky Mabthera Rituxan Gazyva Gazyvaro

F. Hoffmann-La Roche Ltd: Roche renews partnership with Sysmex to deliver haematology testing solutions

F. Hoffmann-La Roche Ltd: Roche renews partnership with Sysmex to deliver haematology testing solutions This successful long-running partnership continues to evolve and bring haematology testing innovations to laboratories, globally The new agreement aims to utilise the IT systems to lead to improved clinical decision making and customer experience Blood disorders have a high impact, not only for patients but for society as a whole, accounting for a third of all central laboratory tests 1 Basel...
United States South Africa New Zealand Nathalie Meetz Jon Kaspar Bayard Daniel Grotzky

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F. Hoffmann-La Roche Ltd: Roche's faricimab meets primary endpoint in two global phase III studies and shows potential to extend time between treatments up to 16 weeks for people with neovascular age-related macular degeneration

(2) Faricimab given at intervals of up to every 16 weeks demonstrated non-inferior visual acuity gains compared to aflibercept given every eight weeks, potentially reducing the frequency of injections and overall burden of treatment Nearly half of people were treated with faricimab every 16 weeks during the first year - the first time this level of durability has been achieved in a phase III study of an injectable eye medicine for neovascular age-related macular degeneration Faricimab is the f...
United States Nathalie Meetz Levi Garraway Daniel Grotzky Jon Kaspar Bayard Karl Mahler

Roche Annual General Meeting 2021: Exercising of shareholder rights via the independent proxy

French Due to the pandemic, the Annual General Meeting of Roche Holding Ltd will take place on 16 March 2021 without the physical presence of shareholders and with only the persons required by the Articles of Incorporation in attendance During the Annual General Meeting, shareholders rights will be exercised exclusively via the independent proxy, without the physical presence of shareholders Basel, 18 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that unfortunately it will n...
United States Nathalie Meetz Daniel Grotzky Patrick Barth Christoph Franz Karsten Kleine

F. Hoffmann-La Roche Ltd: Roche Annual General Meeting 2021: Exercising of shareholder rights via the independent proxy

(2) Due to the pandemic, the Annual General Meeting of Roche Holding Ltd will take place on 16 March 2021 without the physical presence of shareholders and with only the persons required by the Articles of Incorporation in attendance During the Annual General Meeting, shareholders rights will be exercised exclusively via the independent proxy, without the physical presence of shareholders Basel, 18 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that unfortunately it will not ...
United States Nathalie Meetz Daniel Grotzky Patrick Barth Christoph Franz Karsten Kleine

F. Hoffmann-La Roche Ltd: Roche to present updated data confirming Tecentriq in combination with Avastin substantially improves overall survival in people with the most common form of liver cancer

F. Hoffmann-La Roche Ltd: Roche to present updated data confirming Tecentriq in combination with Avastin substantially improves overall survival in people with the most common form of liver cancer 19.2 6.9 18.1 Tecentriq + Avastin (n=133) 24.0 (0.35-0.80) Median follow-up: 15.6 months. CR, complete response; DOR, duration of response; HR, hazard ratio; NE, not estimable; ORR, objective response rate; OS, overall survival; PFS, progression free response; PR, partial response; SD, stable disease...
United States Laura Kulik Nathalie Meetz Levi Garraway Daniel Grotzky Jon Kaspar Bayard

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