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AI Thought – How to Build Superintelligent AI

I spent the last 20 years developing a model of working memory and consciousness. I have laid this out in a series of 25 diagrams illustrating the process and "shape" of thought. Now I am interested in implementing this model within a computer to develop artificial superintelligence.
United Kingdom United States University Of Southern California Baden Wüberg New York Cold Spring Harbor

A multimodal dataset of real world mobility activities in Parkinson's disease

Parkinson’s disease (PD) is a neurodegenerative disorder characterised by motor symptoms such as gait dysfunction and postural instability. Technological tools to continuously monitor outcomes could capture the hour-by-hour symptom fluctuations of PD. Development of such tools is hampered by the lack of labelled datasets from home settings. To this end, we propose REMAP (REal-world Mobility Activities in Parkinson’s disease), a human rater-labelled dataset collected in a home-like se...
Region Flamande United States New York Bruxelles Capitale Nordrhein Westfalen Catalin Ionescu
Source: nature.com

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Conserved and divergent gene regulatory programs of the mammalian neocortex

Divergence of cis-regulatory elements drives species-specific traits1, but how this manifests in the evolution of the neocortex at the molecular and cellular level remains unclear. Here we investigated the gene regulatory programs in the primary motor cortex of human, macaque, marmoset and mouse using single-cell multiomics assays, generating gene expression, chromatin accessibility, DNA methylome and chromosomal conformation profiles from a total of over 200,000 cells. From these data, we show ...
Las Vegas Initiative Cell Census Network International Multiple Sclerosis Genetics Consortium Association For Computing Machinery International Conference On Knowledge Discovery Human Gene Deserts
Source: nature.com

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