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Explainer: mutation and disease in the Folbigg case
The major consequences of genetic mutation.
A gene mutation on chromosomes. Credit: fpm / Getty Images.
The recent petition calling for Kathleen Folbigg’s releasehinges on cutting edge science that has identified a small protein mutation. How can something so miniscule have such a fatal effect, and what is the role of mutation in the Folbigg case?
Genes hold code for proteins, which are the components of our body chemistry that actually do things. Enzymes, hormones and antibodies are all types of proteins.
They are made of chains of amino acids, which join together like a string and fold into a 3D shape that can perform a function.
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