September 20, 1988: Mrs Thatcher makes her famous speech at the College of Europe in Bruges in the first clear sign of frustration at the idea of a federal superpower.
November 28, 1990: Mrs Thatcher is ousted from power amid Tory Party splits over Europe and is replaced by Johns Major.
September 16, 1992: Black Wednesday sees interest rates rocket to 15 percent and the devalued pound is forced out of the ERM, the system intended to stabilise currency values ahead of European monetary union.
November 1, 1993: The Maastricht Treaty establishes the EU, signalling ever closer European cooperation. Britain opts out of the social chapter.
Parliament Square on Januaey 31, 2020 (Image: Getty)