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KUCB will hold a sweatshirt pickup event this Saturday

WATCH: New Orleans Mayor LaToya Cantrell discusses Hurricane Ida aftermath

How to Optimize Success in Clinical Trials of Antidepressants

How to Optimize Success in Clinical Trials of Antidepressants By Paula Jacobsen, Ph.D., and Nick DeMartinis, M.D., Praxis Precision Medicines This is an exceptionally exciting time to be developing therapies for patients suffering from depressive disorders. Advances in antidepressant pharmacology have led to diverse and promising therapeutic options. However, it is important to acknowledge the challenges of conducting clinical trials for major depressive disorder (MDD). Chief among these challenges is the sensitivity of clinical trial methodology for demonstration of efficacy in MDD. A meta-analysis of antidepressant programs that included FDA-approved antidepressant clinical trial data from randomized, double-blind, placebo-controlled acute treatment studies conducted between 1995 and 2008 revealed that only 50% were successful despite the inclusion of only studies that evaluated doses in the approved therapeutic range.

Cecola takes office as Barrington Hills village president

Cecola takes office as Barrington Hills village president New Barrington Hills President Brian Cecola, left, recites the oath of office with help from Judge Samuel J. Betar III. Courtesy of Village of Barrington Hills Former Barrington Hills Village President Martin McLaughlin, right, shows off the parting gifts he received from successor Brian Cecola. Courtesy of Village of Barrington Hills   Updated 5/7/2021 11:39 AM With state Rep. Martin McLaughlin making good on a promise to step down as Barrington Hills' village president, his successor took office this week. Brian D. Cecola was sworn in as the new village president during Monday's board meeting. A former trustee, Cecola defeated Dennis Kelly for the president's chair in last month's election.

Sioux City woman wins $30,000 lottery prize

Sioux City woman wins $30,000 lottery prize Paula Jacobsen won the second top prize in the Iowa Lottery's "Puzzle Payout" scratch game. Lottery officials say Jacobsen purchased her winning ticket at Sarg's Mini Mart, 2329 W. Second St. in Sioux City, and claimed her prize Monday at the lottery's Storm Lake regional office. Puzzle Payout is a $3 scratch game that features 10 top prizes of $30,000.