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Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with ฮฑ-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."
T Ai Pei Vijesh Kumar Yadav Chi Tai Yeh Tung Cheng Chang Kuang Tai Kuo Ying Wei Chen

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Study reveals how tiny tweaks to actin shape our cells

Tiny things matter โ€“ for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Gรถttingen and Warwick investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin.
Andreas Janshoff Institute For Physical Chemistry Nature Communications Physical Chemistry Amino Acid

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