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Amazentis: Meilensteinstudie zeigt, dass das natürliche Molekül Urolithin A die Muskelfunktion und Lebenserwartung von Mäusen mit Muskeldystrophie verbessern kann

Amazentis: Meilensteinstudie zeigt, dass das natürliche Molekül Urolithin A die Muskelfunktion und Lebenserwartung von Mäusen mit Muskeldystrophie verbessern kann
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Federico lunaEpfl johanUrolithin muskelfunktionPeiling luanDavide damicoDevelopment of productsLaboratory of professor drcDevelopment of dmdHealth of miceUniversity lausanneAdministration of urolithinMitophagie induktor urolithinResults havePeriodical sciencePeriodical science translational medicineNew findings

Amazentis: Milestone Study Shows Natural Molecule, Urolithin A, Can Improve Muscle Function and Life Expectancy in Mice With Muscle Dystrophy

Amazentis: Milestone Study Shows Natural Molecule, Urolithin A, Can Improve Muscle Function and Life Expectancy in Mice With Muscle Dystrophy in Science Translational Medicine Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today. The findings, published in Science Translational Medicine, raise hopes that new treatment options could one-day be developed for DMD, an uncurable genetic condition characterized by progressive muscle degeneration. About 1 in 3,500 boys are born with DMD, which usually develops in childhood and significantly reduces life expectancy. The new research carried out at the laboratory of Professor Johan Auwerx, MD, PhD at the Swiss Federal Institute of Technology EPFL and the University of Lausanne in collaboration with scientists at the Swiss life science company Amazentis, highlights the important role that defective mitochondria can play in DMD. The pow

Kostenloser wertpapierhandelFederico lunaPeiling luanChris rinschJohan auwerxUrolithina urolithinDavide damicoSwiss federal institute of technologyUniversity of lausanneAdministration of urolithinDuchenne muscular dystrophyScience translationalDuchenne muscle dystrophyScience translational medicineProfessor johan auwerxSwiss federal institute

Urolithin A shows effective against muscular dystrophy

Credit: © Amazentis / EPFL Auwerx Lab Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today. The findings, published in Science Translational Medicine, raise hopes that new treatment options could one-day be developed for DMD, an uncurable genetic condition characterized by progressive muscle degeneration. About 1 in 3,500 boys are born with DMD, which usually develops in childhood and significantly reduces life expectancy. The new research carried out at the laboratory of Professor Johan Auwerx, MD, PhD at the Swiss Federal Institute of Technology EPFL and the University of Lausanne in collaboration with scientists at the Swiss life science company Amazentis, highlights the important role that defective mitochondria can play in DMD. The powerhouses of cells, mitochondria produce the energy necessary for normal muscle function. But muscle cells taken from both human DMD patien

Peiling luanChris rinschJohan auwerxUrolithina urolithinDavide damicoSwiss federal institute of technologyUniversity of lausanneAdministration of urolithinDuchenne muscle dystrophyScience translational medicineProfessor johan auwerxSwiss federal instituteMuscle dystrophyDavided amicoProject leaderNature medicine