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Moderna, Inc.: Moderna and Merck Announce mRNA-4157 , an Investigational Individualized Neoantigen Therapy, in Combination with KEYTRUDA , Demonstrated Superior Recurrence-Free Survival in Patients with High-Risk Stage III/IV Melanoma Following Complete R

MRNA-4157 (V940) in combination with KEYTRUDA reduced the risk of recurrence or death by 44% compared to KEYTRUDA alone in stage III/IV melanoma patients with high risk of recurrence following complete
United States United Kingdom Mary Beth Woodin Peter Dannenbaum Lavina Talukdar Justine Moore

Moderna, Inc.: Moderna and Merck Announce mRNA-4157/V940, an Investigational Personalized mRNA Cancer Vaccine, in Combination with KEYTRUDA , Met Primary Efficacy Endpoint in Phase 2b KEYNOTE-942 Trial

MRNA-4157/V940, in combination with KEYTRUDA, demonstrated a statistically significant and clinically meaningful reduction in the risk of disease recurrence or death compared to KEYTRUDA monotherapy in
United States United Kingdom Lavina Talukdar Julie Cunningham Mary Beth Woodin Peter Dannenbaum

Cureus | SARS-CoV-2 Antibody Seroprevalence in Patients With Cancer on Systemic Antineoplastic Treatment in the First Wave of the COVID-19 Pandemic in Portugal

At the time of the first wave of the COVID-19 pandemic, patients with cancer were considered to be at high risk of serious illness and had a higher exposure risk since they needed frequent and nondeferrable hospital visits. Serological tests were not routinely used, and seroprevalence in this population was unknown. A single-center, cross-sectional study was developed to determine the seroprevalence of anti-SARS-CoV-2 antibodies (Abs) in patients with cancer undergoing systemic antineoplastic t...
United States Portuguese Health Authority Portuguese National Health Authority Hospital Da Luz Lisboa Ethics Committee Eastern Cooperative Oncology Group Luz Lisboa Ethics Committee
Source: cureus.com

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