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New malaria vaccine strain shows promise in preclinical trials

In a report published on March 21, 2024 in EMBO Molecular Medicine (A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion) investigators at Seattle Children's Research Institute and Sanaria Inc. describe the development of a whole malaria parasite vaccine strain that infects the liver, develops to the late liver stage, and then gets completely stuck and cannot burst out of the liver to cause symptomatic blood infection.

Experts on the best protection against malaria in tropical regions

Travellers who wish to be safe while travelling in tropical regions should protect themselves against the most dangerous animal on the planet, perhaps after the human: The mosquito. Each year 247 million people worldwide get infected with with malaria, according to the 2022 World Malaria Report by the World Health Organisation (WHO). Around 620,000 die, with three-quarters of the number being children under the age of five. Most of the victims are not travellers, but mosquitoes aren't choosy as

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