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Measuring cancer cell state can reveal drug susceptibility

Pancreatic cancer cells can exist in, and transition between, three different cell states, according to new research. These states respond differently to a variety of cancer drugs, and altering the tumor microenvironment can drive tumor cells from one state to another, potentially offering a way to make them more susceptible to a particular drug.
William Hahn Andrew Aguirre Hannah Williams Brian Wolpin Andrew Navia Alex Shalek
Source: mit.edu

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