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February 3, 2021
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This study found that:
Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes in a sewer system.
Concentrations of nine illicit and prescription opioids, the opioid-agonist treatment drugs methadone and buprenorphine, and the opioid-antagonist overdose reversal drug naloxone in wastewater collected at 10 sites in a North Carolina municipality varied by site.
Wastewater-based epidemiology is a novel approach to study opioid exposure at the community level in order to help public health officials better understand and respond to the current opioid crisis in the United States. In a NIDA-sponsored study, Dr. Noriko Endo and colleagues at Biobot Analytics, Inc., in Somerville, Massachusetts, and from other institutions, used a robotic technology pioneered by one of the study s senior investigators, Dr. Mariana Matus, to sample wastewater from municipal sewers and measure the levels of various opioids.