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Navigating Use of Immunotherapy in mNSCLC

Specialists discuss adverse reactions to immunotherapy and explore the importance of CTLA-4 inhibitors in mNSCLC treatment.

United statesAmerican journalSecond line treatmentsCtla 4Poseidon trialCtla 4 inhibitor

Advancements in NSCLC Profiling and Understanding Immunotherapy Resistance

Experts examine primary and acquired resistance mechanisms in immunotherapy, while promoting realistic treatment strategies.

Precision medicineBridging gapsPatients without driver mutationsPd l1High tumor volumeCrisis of diseaseBurden of diseasePlatinum doubletDriver populationPd l1 negativeImmune suppressive microenvironmentPoseidon trialCtla 4 inhibitorMechanisms of resistance

Optimizing the Selection of Novel Therapy for Patients With Advanced NSCLC

Closing out their panel on immunotherapy in non–small cell lung cancer, expert oncologists share key takeaways on the selection of novel therapy in this setting.

Recent updatesTranslating evidenceClinical practiceNovel therapyPatients with advancedLung cancerNon small cell lung cancerTrio therapyImmune checkpoint inhibitorsMetastatic nsclcMetastatic lung cancerCombination therapyClinical trialsSelecting therapySelecting treatmentPdl1 expression

Advanced NSCLC: Interpreting Data From the POSEIDON Trial

A brief review of the POSEIDON trial, which analyzed durvalumab with or without tremelimumab in combination with chemotherapy in advanced NSCLC.

Recent updatesTranslating evidenceClinical practiceInterpreting data fromLung cancerNon small cell lung cancerTrio therapyImmune checkpoint inhibitorsMetastatic nsclcMetastatic lung cancerPoseidon studyPoseidon trialNovel therapyCombination therapy

Role for IO Therapy in Advanced NSCLC With Concomitant KRAS and KEAP1/STK11 Mutations

Key opinion leaders in the field of non–small cell lung cancer management discuss the role of immunotherapy in patients with concomitant KRAS and KEAP1/STK11 mutations.

Recent updatesTranslating evidenceClinical practiceLung cancerNon small cell lung cancerTrio therapyImmune checkpoint inhibitorsMetastatic nsclcMetastatic lung cancerKras stk11Kras keap1Poseidon studyPoseidon trialNgs testingNext generation sequencingMolecular testing

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