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Structure of DNA is found to be actively involved in genome regulation

University of Seville The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later. The paper that has now been published by the team led by Felipe Cortรฉs, head of the DNA Topology and B...
Spain General Silvia Jimeno Gonz Felipe Cort Andalusian Centre For Molecular Biology University Of Seville Health Institute

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