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Immune cell switch helps send inflammatory bowel disease into remission

Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, are unpleasant, chronic conditions with few treatment options. Now, researchers may have found a way to potentially “switch on” the body’s natural tissue repair system.

Novel method instructs immune cells to help repair damaged tissues in the intestine

Novel method instructs immune cells to help repair damaged tissues in the intestine A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University. This opens the way for more effective treatment of inflammatory bowel disease, including ulcerative colitis and Crohn s disease. The study was carried out on humans and mice. When functioning correctly, the immune system protects against harmful agents such as bacteria that get into the body. But in conditions such as inflammatory bowel disease (IBD), the immune system attacks the tissues that line the gut, forming ulcers and causing pain and discomfort. Nearly 3.9 million women and 3.0 million men are living with IBD worldwide, and the number of cases is rising.

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