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Dr Stein on the Development of Targeted Therapies in Splicing Mutant Hematologic Malignancies

Eytan M. Stein, MD, discusses the ongoing development and investigation of therapies targeting splicing mutations in hematologic malignancies.

Eytanm steinDivision of hematologic malignanciesMemorial sloan kettering cancer centerLeukemia serviceProgram for drug development in leukemiaDrug developmentHematologic malignanciesAim leukemiaOnclive tvEmavusertib formerly ca 4948Clk inhibitor

Syndax Pharmaceuticals (SNDX) to Initiate NDA Submission of Revumenib in Relapsed/Refractory KMT2Ar Acute Leukemia Under FDA s Real-Time Oncology Review Program

Syndax Pharmaceuticals (SNDX) to Initiate NDA Submission of Revumenib in Relapsed/Refractory KMT2Ar Acute Leukemia Under FDA s Real-Time Oncology Review Program
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Michaela metzgerEytanm steinDrug administrationProgram for drug development in leukemiaSyndax pharmaceuticals nasdaqDuring the companyOncology centerSyndax pharmaceuticalsNew drug applicationReal time oncology reviewTherapy designationChief executive officerDrug developmentMemorial sloan kettering cancer centerPrincipal investigator

Auron Establishes Premier Scientific Advisory Board to Support the Advancement of its AI-Powered Platform and Pipeline Targeting Cellular Plasticity in Cancer

Auron Establishes Premier Scientific Advisory Board to Support the Advancement of its AI-Powered Platform and Pipeline Targeting Cellular Plasticity in Cancer
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United statesMassachusetts institute of technologyDana farber cancer instituteProvence alpes côd azurUnited kingdomFrance generalRichard chesworthMikhail misha roshalCharlesm rudinShin san michael suVander heidenLaurence joseph dineenMatthew vander heidenSylvia hassenfeldEytanm steinTed williams

Foghorn Therapeutics Announces FDA Has Lifted Clinical Hold on Phase 1 Study of FHD-286 in Relapsed and/or Refractory AML/MDS Patients

- Plan to Initiate a Phase 1 Study of FHD-286 in Combination with Decitabine or Cytarabine in Relapsed and/or Refractory AML Patients in Q3’2023 - Clinical and Pre-Clinical. | June 5, 2023

United kingdomUnited statesKarin hellsvikMartin tallmanEytan steinHans vitzthumMichael lampeAdrian gottschalkTherapeutics incCompany annual report on formExchange commissionDrug administrationFoghorn therapeutics incProgram for drug development in leukemiaLeukemia servicePre clinical data suggest

Acute leukemia: Menin-targeting drug revumenib aids remission in trial

A treatment called revumenib, which inhibits the protein menin, showed promising results for individuals with acute leukemia, and aided remission in 30% of study participants.

United statesEytanm steinGhayasc issaDivision of cancer medicineLeukemia serviceUniversity of texas md anderson cancer centerProgram for drug development in leukemiaDepartment of leukemiaSyndax pharmaceuticalsDrug developmentHematologic malignanciesMemorial sloan kettering cancer centerMedical newsCancer medicine