Deaths in the bay area San Francisco and santa clara are both reporting more than 200 new cases alameda and contra costa counties more than a 100 solano 80 send the tail napa marin counties all have about 20 new cases, but every county except San Francisco and napa have reported at least one new death from the virus. And the numbers again could be even higher because of a technical problem which has led to an undercount in other cases across the state. While the latest case numbers do indicate the virus is spreading again the numbers could be higher than we think kron fours rob fladeboe joins us live in san jose with the latest rob. Thats right catherine. Well, the 2 burning questions right now as you said number one just how much higher might the case count be a number 2. What are we going to do about it the south face Top Health Official says the answer to both of those questions is quote we just dont know. Heres more. You dont know if our cases are rising. Plateauing or decreasing S
Purpose: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression.
Methods: Transmission electron microscopy (TEM) was used to examine cellular uptake of nHAp. Cell viability was determined using CCK-8 assay kit. Mitochondrial impairment and reactive oxygen species were detected by TEM and fluorescence dye staining, respectively. Cell apoptosis was detected by Western blot analysis and Annexin V staining. Mouse model of VC was built via applying nHAp on the surface of abdominal aorta. Calcification was visualized by Alizarin red and von Kossa staining.