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John Thwaites, Liam Smith, Salim Abdool Karim, Yanis Ben Amor New COVID variants have changed the game, vaccines will not be enough At the end of 2020, there was a strong hope that high levels of vaccination would see humanity finally gain the upper hand over SARS-CoV-2, the virus that causes coronavirus disease 2019 COVID-19. In an ideal scenario, the virus would then be contained at very low levels without further societal disruption or significant numbers of deaths. But since then, new “variants of concern” have emerged and spread worldwide, putting current pandemic control efforts, including vaccination, at risk of being derailed.

South africaUnited kingdomChris bullenSalim abdool karimSusan michieJeffreyv lazarusJohn thwaitesLiam smithJohnn lavisYanis ben amorSustainable development earth institute at columbia universityMonash universityCommission taskforce on public healthMonash sustainable development instituteChris bullen is professor of public healthProgram of research