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IMAGE: This study has found that KNDy neurons are key to controlling ovarian function in mammals. These neurons express signalling molecules (peptides) in the brain that stimulate pulses of a hormone. view more
Credit: Sho Nakamura
Gonadotropins are any hormones that are released from the anterior pituitary to stimulate the gonads, or sex glands, to carry out their reproductive functions. The gonadotropin-releasing hormone (GnRH) is therefore fundamental for mammalian reproduction. In a healthy reproductive system GnRH is produced by the brain in pulses. Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism controlling the release of gonadotropins, which is a kind of reproductive disorder associated with the hypothalamus.