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First-in-Class PARP1 Selective Inhibitor Saruparib Shines in Phase 1 Trial of Advanced Solid Tumors

Timothy Yap, MBBS, PhD, FRCP, discusses encouraging data seen with the first-in-class PARP1 selective inhibitor saruparib in solid tumors and how the agent is being further investigated.
United States Timothy Yap Therapeutics Discovery Division Translational Research University Of Texas Md Anderson Cancer Center Khalifa Institute For Personalized Cancer Therapy

Precision Oncology Innovator SimBioSys and General Inception Announce Strategic Partnership to Accelerate Cancer Drug Development

PhenoScope can cut drug development time and costs significantly, while delivering safer & more effective therapy for cancer patients It can provide more precise patient dosing to reduce side effects, increase efficiency and reduce wastage CHICAGO, IL & PALO ALTO, CA – 3 April 2024 – Si...
United States Venkat Reddy Tushar Pandey Drug Administration Oncology Center Simbiosys Inc General Inception

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Cancer patients push back against drugs' harsh side effects

Cancer patients and doctors have ignited a movement to radically change how new cancer drugs are tested to make them more tolerable. Harsh side effects from powerful cancer drugs have long been accepted as a trade-off for living longer. Now, patients and doctors are questioning whether all that suffering is necessary. The U.S. Food and Drug Administration is pushing drugmakers to do a better job at finding the lowest effective dose, even if it takes more time. One group is planning a study to te...
Mount Whitney United States Timothy Yap Jill Feldman Lesley Kailani Glenn Patricia Lorusso

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