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Cryo-EM Provides New Insights into Acute Myeloid Leukemia

To overcome the hurdle of two technologies used to determine the structure and function of proteins—X-ray crystallography and cryogenic electron microscopy— researchers at Stanford University's Schools of Medicine and Engineering and the Department of Energy's SLAC National Accelerator Laboratory have used a kind of molecular cage to stabilize certain medium-sized proteins so they can be imaged with cryo-EM.
United States Kathleen Sakamoto Soichi Wakatsuki Simulation Enable The Development Of Peptide Therapeutics Department Of Energy Stanford School Of Medicine

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ITM and Navigo Proteins Announce Research Collaboration to Develop FAP-targeting Radionuclide Therap

  Companies will work toward accessing a novel strategy for breaking the tumor microenvironment by combining ITM’s high-quality radioisotopes with Navigo’s precise target-specific affinity ligands against the fibroblast activation protein (FAP)GARCHING/MUNICH, Germany and HALLE/SAALE, Germany, December 02,...
Valeria Fisher Ben Orzelek Steffen Schuster Priyanka Sahasrabudhe Julia Hofmann Susanne Karlsson Henning Afflerbach

Plasmid DNA vaccines induce effective antibody responses against SARS-CoV-2 in mice

Researchers in the United States and China have developed plasmid DNA immunogens that induce effective antibody responses in mice against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).
United States University Of California San Diego Maurizio Zanetti Sally Robertson Academy Of Sciences Jolla Institute For Immunology

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