Ion and lipid transporters specialize for their niche
Cell viability require that a variety of functions at the cell membrane are maintained properly. P-type ATPases translocate substrates across the membrane, and they have evolved into different types taking care of specific substrates within a diverse range. Now, key structural aspects have been described on how two different types of P-type ATPases -- a Ca2+ transporting Ca2+-ATPase and a lipid transporting P4-ATPase - have adapted to different substrates and physical environments.
Josepha Lyons Jacob Lauwring Andersen Thomas Boesen Milena Timcenko Sara Basse Hansen Caroline Neumann
Source: eurekalert.org