Nanomedicine targets cardiovascular disease
Michigan State and Stanford researchers have upgraded their Trojan horse therapies designed to fight one of the world’s leading causes of death.
Led by Bryan Smith, an associate professor in MSU’s Department of Biomedical Engineering, the team is building on its nanoscopic tubules that carry drugs to fight atherosclerotic plaques involved in cardiovascular disease.
With the help of some crafty chemistry, the team has enabled the tubes to sense when they’ve successfully entered a cell to release their therapeutic payloads. The team, including first author Yapei Zhang, a postdoctoral fellow in Smith’s lab, published this work online on Nov. 6, 2020, in the journal Nano Research.