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FDA's acetaminophen-opioid mandate linked to reductions in acute liver failure

An FDA mandate limiting acetaminophen in medications combining acetaminophen and opioids was associated with a reduction in serious liver injuries, a recent study in JAMA found.According to Babak J. Orandi, MD, PhD, MSc, an assistant professor of surgery at the University of Alabama at Birmingham, and colleagues, the mandate — first introduced by the FDA in 2011 and requiring compliance by
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Source: healio.com

Patients with asthma have more favorable COVID-19 outcomes in inner-city population

SAN ANTONIO — Patients with asthma in an inner-city population had more favorable COVID-19 outcomes than patients who did not have asthma, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.“Few studies have examined COVID-19 infection specifically in inner-city patients with asthma,” Mydalyn D. Beronilla, MPH, clinical
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Source: healio.com

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Partnership expands to develop new prescription digital therapeutic for schizophrenia

Boehringer Ingelheim and Click Therapeutics have announced the launch of an expanded collaboration for development and commercialization of a second prescription digital therapeutic for those diagnosed with schizophrenia. According to a release from Boehringer, the collaboration intends to produce a novel mobile application that combines multiple clinically validated therapeutic interventions
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Source: healio.com

Novel agent demonstrated tolerability, clinical response in patients with advanced NSCLC

For patients with advanced non-small cell lung cancer who showed an inadequate response to front-line immunotherapy checkpoint inhibitors and chemotherapy, the addition of CAN-2409 was well-tolerated. The preliminary clinical data of CAN-2409, a replication-deficient adenoviral gene construct that delivers the thymidine kinase gene, was presented at ASCO Annual Meeting.
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Source: healio.com

More data needed on sex, gender differences in stroke treatment, outcomes

Endovascular therapy is now a standard treatment for select patients with severe ischemic stroke to improve the likelihood of functional recovery; yet there remains a paucity of research on outcomes by sex and gender.The American Heart Association in June published a scientific statement on sex- and gender-related differences in endovascular stroke treatment in Stroke. The statement
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Source: healio.com

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