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No association found between mode of birth, risk for food allergy

Whether infants were born via vaginal or cesarean delivery did not lead to meaningful differences in likelihood of food allergy at age 12 months, according to a study published in The Journal of Allergy and Clinical Immunology. The lack of likelihood persisted regardless of onset of labor or whether cesarean deliveries were elected or emergent, Anne Currell, MEpi, a researcher in population
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Source: healio.com

Lacosamide safe, effective for childhood epilepsy with centrotemporal spikes

Lacosamide monotherapy for the treatment of childhood epilepsy with centrotemporal spikes was well tolerated and resulted in significantly reduced seizures, according to a study published in Brain and Development. “Childhood epilepsy with centrotemporal spikes is an age-limited epilepsy syndrome,” Tohru Okanishi, MD, PhD, associate professor of child neurology at Tottori University in
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Black patients 'not caught up' to whites in early-onset CRC survival over 20-year period

SAN DIEGO — Five-year relative survival for early-onset colorectal cancer improved over a 20-year period only among white patients, with no improvements for Black, Asian or Hispanic patients, per data at Digestive Disease Week 2022.“Our most stunning finding was that even over a 20-year span, Blacks had not caught up to whites in surviving early-onset CRC,” Timothy A. Zaki, MD,
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Low-cost scoring system informs HBV treatment eligibility in resource-limited countries

SAN DIEGO — A new, low-cost scoring system called TREAT-B accurately determined treatment eligibility for patients with hepatitis B virus, particularly where DNA assays are unavailable, according to research. “Major international guidelines have recommended the criteria for initiating treatment in patients with chronic hepatitis B infection. However, the hepatitis B DNA assay is not
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Anatomic MCL repair, reconstruction may have equivalent radiographic outcomes

SAN FRANCISCO — Results presented here showed anatomic-based medial collateral ligament repair and MCL reconstruction may be equivalent based on objective knee laxity, but MCL reconstruction had better subjective outcomes. Nicholas N. DePhillipo, PhD, ATC, and colleagues randomly assigned 54 patients with grade 3 MCL tears with or without concomitant ACL injuries to undergo either an
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Statins may protect against acute cholangitis in primary sclerosing cholangitis

SAN DIEGO — Statin therapy decreased the risk for developing acute cholangitis among patients with primary sclerosing cholangitis, according to research presented at Digestive Disease Week 2022. “Primary sclerosing cholangitis [PSC] is a cholestatic biliary disease whose analysis and underlying biology remains fairly poorly understood,” Chiraag Kulkarni, MD, internal
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Source: healio.com

Q&A: Non-criteria manifestations of pediatric APS common yet 'under-recognized'

Peer-reviewed papers on pediatric antiphospholipid syndrome do not appear very often.However, when they do, they can be incredibly useful for rheumatologists who find themselves trying to diagnose and manage a patient with this rare and complicated condition, which can present in myriad ways.
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FDA grants marketing approval for neuromodulation device to reduce fibromyalgia symptoms

The FDA has granted De Novo authorization for NeuroMetrix to market its Quell neuromodulation device as an aid for reducing fibromyalgia symptoms in adults with high pain sensitivity, according to a company press release.“There is an unmet need for effective and safe fibromyalgia treatments,” Shai N. Gozani, MD, PhD, CEO of NeuroMetrix, said in the release. “Receiving this De
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HHS to establish center of excellence on social media, mental wellness

HHS, through the Substance Abuse and Mental Health Services Administration, has announced that it will provide $2 million in funding to establish a national center of excellence on social media and mental wellness. The HHS said in a press release that the center will develop and disseminate information, guidance and training on the impact that social media use has on children and youth, while
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Lebrikizumab shows promise in adolescents with uncontrolled asthma

SAN FRANCISCO — Lebrikizumab reduced exacerbations in adolescents with uncontrolled asthma and had a favorable safety profile, according to results of the ACOUSTICS study.The study, which was stopped early by the sponsor, showed a greater treatment effect with the higher dose of lebrikizumab studied.
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