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SEATTLE — In a first-in-human study, participants with paralysis who received an endovascular brain-computer implant were able to effectively operate a computer, researchers reported at the American Academy of Neurology annual meeting. Douglas J. Weber, MS, PhD, professor at Carnegie Mellon University Neuroscience Institute and College of Engineering, and colleagues assessed the

WASHINGTON — Tranexamic acid administered intravenously before and after noncardiac surgery lowered the risk for life-threatening, major and critical organ bleeding compared with placebo, according to results of the POISE-3 trial.Although 1 g IV bolus tranexamic acid cut bleeding risk at 30 days, noninferiority was not established for the composite vascular outcome compared with placebo,

The 2022 American College of Cardiology Scientific Session will be held live in Washington, D.C., from April 2 to 4, and virtually, with 39 late-breaking trials and featured clinical research presentations.“I am most excited about the fact that we are back to live education ... in the city that is the home of the ACC Heart House. So, welcome back and welcome home,” Pamela B. Morris,

Convalescent plasma, when administered within 9 days of symptom onset in patients with COVID-19, may reduce the risk for hospitalization, according to data published in The New England Journal of Medicine. “While everyone was focused on treating people in the hospital after progression of disease, we saw the need to keep people out of the hospital rather than wait until they were near

Large amounts of tau proteins in the brain affected memory function only when amyloid protein burden was also high in those with Alzheimer’s disease, data suggests in a study published in Brain. “It has long been known that deposits of tau proteins in the so-called hippocampus and in neighboring brain areas impair memory,” Emrah Düzel, MD, director of the Institute of

More than one-third of high school students in the United States reported experiencing poor mental health during the COVID-19 pandemic, according to survey results published in MMWR.

The amygdala, which is enlarged in children aged 2 years who are diagnosed with autism spectrum disorder, appears to accelerate in growth in the first 6 to 12 months of life, researchers reported in The American Journal of Psychiatry. “This suggests that early, presymptomatic brain changes in infancy may represent a cascade of linked brain and behavior changes that lead to the emergence of

Iberdomide, a novel oral cereblon modulator, was superior to a placebo only in patients with systemic lupus erythematosus who received the highest dose in a phase 2 trial, albeit with a high incidence of adverse events, according to data.

Two servings of avocado per week, compared with not eating any avocado, was associated with lower risk for CVD and CHD, but not stroke, researchers reported.According to data published in the Journal of the American Heart Association, replacing half of one daily serving of margarine, butter, egg, yogurt, cheese or processed meats with avocado was tied to lower risk for CVD.

The COVID-19 pandemic substantially affected the pediatric oncology workforce, leading to physical, psychological and financial strain, according to results of a survey study published in Cancer. “This survey is unique, as it captures the global impact of the pandemic in the context of a discipline, ie, pediatric hematology/oncology,” Lorena V. Baroni, MD, of the hematology/oncology