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March 16, 2022
Nephrology News and Issues | In the United States, the annual rate of growth in incident patients with end-stage kidney disease has slowed. However, patients selecting home dialysis for the first time increased 85.6% from 2007 to 2016 and those choosing peritoneal dialysis grew 60.2% in that timeframe, according to recent data from the U.S. Renal Data System.
March 16, 2022
Nephrology News and Issues | For the first time in 2 years, the National Kidney Foundation Spring Clinical Meetings will take place live, organizers report. Tara I. Chang, MD, MS, said attendees are looking forward to the change.“I think many people are ready; we all miss that in-person interaction,” Chang, the 2022 Spring Clinical Meetings (SCM22) conference chair and division chief and associate professor of
March 15, 2022
Breast arterial calcification seen on a routine mammogram may independently predict atherosclerotic CVD and global CVD risk for postmenopausal women, according to research published in Circulation: Cardiovascular Imaging.Research suggests breast arterial calcification, a common incidental finding in mammography, may be associated with angiographic CAD and CV outcomes, and such calcification could
March 15, 2022
Obesity and elevated central adiposity were associated with increased risk for future cancers, including gastrointestinal and gynecologic cancer, researchers reported.In addition, elevated circulating C-reactive protein levels were associated with increased risk for future overall, colorectal and lung cancer, according to data published in JACC: CardioOncology.
March 15, 2022
Prescriptions dispensed for apixaban beyond 90 days after hospitalization resulted in a lower rate of hospitalization for recurrent venous thromboembolism compared with warfarin beyond 90 days, according to study results published in JAMA. However, researchers observed no significant differences in risk for hospitalization for major bleeds and no significant differences for comparisons between
March 15, 2022
Gut dysbiosis is more frequent in patients with ankylosing spondylitis, compared with controls, and is associated with worse axial spondyloarthritis disease activity and physical function, according to data.“The link between spondyloarthritis (SpA) and inflammatory bowel disease (IBD) is well recognized,” Jonas Sagard, of Lund University, in Sweden, and colleagues wrote. “IBD
March 14, 2022
While in-person visits for patients with cystic fibrosis decreased from 2019 to 2020 during the COVID-19 pandemic, a new study found no evidence of worse lung disease, nutrition or increased risk for pulmonary exacerbations.“The CF Foundation recommends frequent clinical encounters to monitor for progression of lung disease, surveillance of respiratory microbiology and monitoring for cystic
March 14, 2022
Tofacitinib for psoriatic arthritis is efficacious in most patient-reported and clinical endpoints over time, and shows shorter initial and meaningful response times versus switching from placebo to the drug at month 3, noted researchers. “The efficacy and safety of oral tofacitinib 5 mg or 10mg twice daily (BID) or adalimumab (40mg administered subcutaneously once every 2weeks [Q2W]) have
March 10, 2022
The FDA granted orphan drug designation to NTLA-5001 for treatment of adults with relapsed or refractory acute myeloid leukemia. NTLA-5001 (Intellia Therapeutics) is an autologous T-cell receptor (TCR)-engineered T-cell therapy. The agent uses ex vivo CRISPR gene editing to insert a TCR on a patient’s T cells that targets the Wilms’ tumor 1 (WT1) antigen within and on the surface
March 10, 2022
Concussion was linked to increased risk for mental health issues, psychiatric hospitalization and self-harm among youths aged 5 to 18 years, according to results of a population-based retrospective cohort study. “Few studies have rigorously examined associations between concussion and risk of psychopathology, new onset of psychiatric disorders or long-term [mental health problems],”