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The American College of Rheumatology has released two updated guideline papers for the treatment and management of juvenile idiopathic arthritis, according to a press release. “As rheumatologists, our patients and caregivers expect us to review the literature and weigh the evidence so that we can suggest the best treatments, while also considering their preferences,” Karen Onel, MD,

Home confinement and distance learning significantly increased the number of hospital visits for myopia at a university hospital in Istanbul, although no correlation was found with myopia progression.The increasing prevalence of myopia is a major public health issue worldwide. Global estimates suggest a burden of 5 billion people affected by 2050. Home confinement and implementation of

Implementation of treatment for alcohol withdrawal symptoms without benzodiazepines was associated with decreased use of the drug and favorable outcomes, according to a quality improvement study published in JAMA Network Open.“While BZDs are associated with effective reductions in [alcohol withdrawal syndrome] AWS symptoms, they are also associated with adverse effects, including excessive

Outpatient antibiotics improved outcomes for patients with injection drug use-associated infective endocarditis compared with patients who received inpatient IV therapy, according to a study. Between 2003 and 2016, hospitalizations associated with infective endocarditis increased from 16 per 100,000 adults in to 22 per 100,000 adults, and 10% of the hospitalizations are now a result of injection

Among patients with in-hospital cardiac arrest, those with COVID-19 had worse rates of survival and return of spontaneous circulation compared with those who did not, according to a research letter published in JAMA Network Open.However, those with COVID-19 and in-hospital cardiac arrest in this cohort, spanning March to December 2020, had a higher rate of survival than those with COVID-19 and

Adding romidepsin to busulfan and fludarabine reduced incidence of relapse among patients receiving allogeneic stem cell transplant for aggressive T-cell malignancies, according to results of a phase 1/phase 2 study.The three-drug combination also mitigated the poor outcomes of patients with measurable residual disease prior to transplant, with toxicities similar to busulfan and fludarabine

Exposure to burning oil and gas was associated with newly detected hypertension among individuals who worked on response and cleanup for the Deepwater Horizon oil spill, researchers reported.“The Deepwater Horizon (DWH) explosion on April 20, 2010, caused the largest marine oil spill in U.S. history,” Richard K. Kwok, PhD, acting chief of staff in the office of the director and staff

The FDA has denied a New Drug Application for oleogel-S10 for the treatment of the cutaneous manifestations of dystrophic and junctional epidermolysis bullosa, Amryt Pharma announced in a press release.In a complete response letter, the FDA requested additional efficacy evidence for oleogel-S10.

PHOENIX — Patients with alpha-gal syndrome reported many physical and mental effects along with a profound quality-of-life impact, according to survey results presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.Understanding the vast range of symptoms that can indicate alpha-gal syndrome (AGS) — the first known carbohydrate-based allergy to

Diastolic dysfunction is an independent risk factor for increased mortality risk among patients with systemic sclerosis, according to a study published in Arthritis & Rheumatology.“[Diastolic dysfunction (DD)] is independently associated with an increased risk of mortality in patients with SSc,” Alicia M. Hinze, MD, MHS, an assistant professor in the division of rheumatology at