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One-year results of four phase 3 trials of faricimab showed safety and efficacy comparable to aflibercept in the treatment of wet age-related macular degeneration and diabetic macular edema, with potentially longer treatment intervals.Across all four pivotal studies, about 50% of patients treated with faricimab (Genentech) were able to achieve a treatment interval of 16 weeks, and more than 70%

Disease-modifying antirheumatic drugs did not appear to be linked to a lower risk for Parkinson’s disease among individuals with rheumatoid arthritis, according to results of a nested case-control study published in Neurology.“Rheumatoid arthritis has been linked to lower risk of Parkinson’s disease (PD), although some studies have also observed an increased risk of PD in people

A three-step support strategy significantly reduced prolonged grief symptoms among relatives of patients dying in the ICU, according to results of a cluster randomized trial published in The Lancet. “Many studies have shown that communication with ICU clinicians is one of the most highly valued aspects of care and has a major effect on relatives’ experience throughout the

Clinical-stage biopharmaceutical company Mind Medicine Inc. announced the FDA cleared its investigational new drug application to proceed with a phase 2b dose-optimization of MM-120 for treating generalized anxiety disorder. The treatment is a pharmacologically optimized form of LSD in development for generalized anxiety disorders and other brain-based disorders, the company said in a press

Poor indoor air quality and housing conditions were associated with respiratory issues in young First Nations children living in Northern Ontario, researchers reported in the Canadian Medical Association Journal.“Surveys have found that more than 24% of [First Nations] and Inuit housing is overcrowded or in need of major repairs or both, compared with 6% elsewhere in Canada. Issues related

In Canada, pediatric ED visits due to cannabis exposure significantly increased after recreational cannabis was legalized, according to recent data. The website for the government of Canada states that the country legalized sales of fresh cannabis, dried cannabis, cannabis oil, cannabis seeds and cannabis plants in 2018. One year later, the sale of edible cannabis products, cannabis extracts and

The COVID-19 pandemic has changed how we approach health care in the United States in myriad ways, especially for vulnerable populations.

Commercial-stage bioelectronic medicine company electroCore Inc. announced its noninvasive vagus nerve stimulation intervention for migraine prevention reduced the number of monthly headache days. Results of the multicenter, randomized, double-blind, sham-controlled trial conducted across 27 sites in the U.S. were published in Cephalalgia. Researchers enrolled 336 individuals and randomly

Overall satisfaction with telehealth visits was high for pediatric rheumatology patients and their caregivers during the COVID-19 pandemic, though there may be areas for improvement, according to data published in Pediatric Rheumatology.“While telehealth has been examined in adult rheumatology and other pediatric subspecialties, studies characterizing and assessing pediatric rheumatology

Text messaging showed promise as a surveillance tool to identify acute respiratory infections over a 5-year period in New York City, researchers found.