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No Surprises Act faces multiple lawsuits against billing dispute provision

The No Surprises Act, which officially took effect Jan. 1 as a way to protect patients from unexpected medical bills, already faces several lawsuits from health care organizations.The bill was passed by Congress in 2020 as part of the coronavirus relief package. It was designed to safeguard patients against surprise out-of-network care costs.
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Source: healio.com

Integrated clinical trial data show efficacy, safety of nasal spray for dry eye

Integrated data from the phase 2 ONSET-1 and phase 3 ONSET-2 clinical trials showed that OC-01 nasal spray effectively improves endogenous basal tear production in a heterogeneous dry eye disease population.The results of this analysis were presented in a poster session at the American Academy of Ophthalmology meeting by John Sheppard, MD.
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Source: healio.com

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CDC: Geographic, socioeconomic factors linked to suicidal behaviors in adults

Suicidal thoughts and behaviors in the U.S. adult population arise due to several factors, including geography, demographics, socioeconomic status and cultural setting, according to study findings published in MMWR.“Self-directed violence is a major public health issue in the United States. It includes a range of behaviors, from nonsuicidal intentional self-harm (ie, behavior in which the
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Source: healio.com

FDA grants orphan drug designation for oral narcolepsy treatment

The FDA granted orphan drug exclusivity for JZP258, an oral solution for the treatment of narcolepsy symptoms, according to the agent’s manufacturer. JZP258 (Jazz Pharmaceuticals plc), also known as Xywav, is a low-sodium oxybate aimed at correcting cataplexy and excessive daytime sleepiness in patients aged as young as 7 years, as well as narcolepsy in adults.
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Source: healio.com

Early C-reactive protein 'not a good biomarker' for canakinumab impact on gout flares

Early reduction in high-sensitivity C-reactive protein is “not a good biomarker” for canakinumab’s protective impact on future gout flares, according to data published in Arthritis Care & Research.However, results from a prevalent gout subgroup suggest there may be a potential role for using reduced early high-sensitivity CRP as a biomarker for interleukin-1 inhibition
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Source: healio.com

Q&A: Improved Adherence to Topical Drugs Boosts Treatment Outcome

Healio Psoriatic Disease | Drug adherence is one of the biggest barriers to topical psoriasis treatment. Messy vehicles, multiple daily applications and cost factors can all impact a patient’s adherence rates. Mathias Tiedemann Svendsen, MD, PhD, specialist in dermato-venereology and clinical assistant for the department of dermatology and allergy center at Odense University Hospital in Denmark, regularly conducts
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Source: healio.com

Hepatic steatosis observed in most adults with obesity, diabetes

Nearly 80% of U.S. adults with obesity and diabetes have hepatic steatosis and an increased risk for advanced fibrosis, according to study findings published in Obesity. “In people with diabetes, even those in the early stages of obesity, the majority had steatosis, and the prevalence of fibrosis was high,” Kenneth Cusi, MD, FACP, FACE, chief of the division of endocrinology,
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