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Mosunetuzumab more than quadrupled the complete response rate among patients with relapsed or refractory follicular lymphoma, according to results of a pivotal phase 2 study.Seventy-six percent of patients in the study who had a complete response were free of disease-related complications and did not require further treatment 1 year after receiving mosunetuzumab (Genentech).

Healio Gastroenterology presents the following report on the top 10 peer-tested articles from November 2021.Stories include meeting news coverage from ACG and GI Outlook as well as research in GERD, defecatory dysfunction, colorectal cancer screening and more.

Although same-day surgery may be safely performed in select patients and with experienced surgical teams, there are controversies that need to be addressed, according to a presenter here.In his keynote address at the Current Concepts in Joint Replacement Winter Meeting, Kevin J. Bozic, MD, noted previously published literature comparing inpatient and outpatient total joint hip and knee surgery

The number of psychiatrists who provided psychotherapy significantly declined between 1996 and 2016, according to study results published in American Journal of Psychiatry.“Between 1996–1997 and 2004–2005, the proportion of U.S. outpatient psychiatrist visits involving psychotherapy declined from 44.4% to 28.9%,” Daniel Tadmon, MPhil, and Mark Olfson, MD, MPH, both of

Healio spoke with Grace Cheng, PharmD, APh, BCACP, BCGP, about what types of medication may have lowered efficacy among patients with obesity, how to inform patients about these medications and more.

Anatomic, kinematic and functional alignment for total knee replacement may have clear and consistent advantages over mechanical alignment, according to a presenter at the Current Concepts in Joint Replacement Winter Meeting. According to Mark W. Pagnano, MD, use of anatomic, kinematic and functional alignment strategies for TKA may provide easier balancing of the knee.

Metformin did not improve outcomes for most patients with early breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.Results of the Canadian Cancer Trials Group MA.32 trial showed no improvement in invasive DFS, OS or other outcomes among patients with moderate- or high-risk ER/PR-positive or ER/PR-negative breast cancer, suggesting metformin should not be

Patients with nonalcoholic fatty liver disease and liver-involved fibrosis frequently had a cholestatic pattern that increased the risk for liver-related events, according to a presentation at The Liver Meeting Digital Experience.“While mild to moderate cytolysis with raised aminotransferase blood levels is a common feature of nonalcoholic fatty liver disease, an increase of [alkaline

Men and women with ischemic stroke had improved functional outcomes in the past 2 decades, likely due in part to the development of acute reperfusion therapy, according to results of a prospective, registry cohort study.“In Japan, both the age-adjusted incidence and mortality of stroke decreased drastically during the past half century, but these trends slowed in recent decades,”

Intensive lifestyle therapy in children and adolescents with nonalcoholic fatty liver disease led to significant weight loss and improvements in liver steatosis and fibrosis, according to study results. “The implementation of a structured lifestyle program is a promising therapeutic approach for pediatric NAFLD,” Sander Lefere, MD, PhD, of the hepatology research unit in the