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Single-dose synthetic psilocybin improves the core symptoms of treatment-resistant depression, while other frequently measured parameters only contribute noise to the outcome, phase 2 data show.

ECT in older patients with refractory depression and bipolar disorder has been linked to cognitive improvement, allaying fears that the treatment could have a deleterious impact in this patient population.

Repeated IV ketamine infusions were associated with improved psychosocial functional impairments in adults with treatment-resistant bipolar disorder.

Approximately one-third of patients with MDD benefitted substantially from treatment with an acute induction course of ketamine infusions.

Bilateral TBS achieved noninferior symptom reduction compared with standard bilateral rTMS in older adults with treatment-resistant depression.

Bilateral TBS achieved noninferior symptom reduction compared with standard bilateral rTMS in older adults with treatment-resistant depression.

This systematic review to support the 2022 US Preventive Services Task Force Recommendation Statement on screening for depression and suicide risk in children a

Poor treatment outcomes among patients with major depressive disorder may be associated with disturbed rhythmicity of sleep, according to a study.

Poor treatment outcomes among patients with major depressive disorder may be associated with disturbed rhythmicity of sleep, according to a study.

Youth who experienced bullying were found to be at increased risk for psychopathology, however, resilience was observed to be a protective factor.