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Big Drops in LDL Cholesterol With Inclisiran, but US Clinicians Still Await Drug's Approval

March 03, 2021 A pooled analysis of clinical trials testing inclisiran (Novartis) that confirms the agent’s potent effects on LDL cholesterol has now been published. Yet the small interfering RNA (siRNA) molecule, which has since been approved in Europe, remains in limbo in the United States. The analysis, combining patients from three ORION trials, was first presented at the virtual 2020 American College of Cardiology Scientific Session and was published this week in the Journal of the Ame...
United States Baylor College Of Medicine Vijay Nambi Sanofi Regeneron R Scott Wright Md Baylor College Of Medicine
Source: tctmd.com

Blood plasma with high levels of COVID-19 antibodies reduced the number of patient deaths by 25%

Convalescent plasma therapy is when the liquid portion of blood is taken from a recovered coronavirus patient It is transferred into a sick patient in hopes they will develop the antibodies needed to fight off the infection  Researchers looked at 3,082 hospitalized COVID-19 patients who received  blood plasma transfusions Just 22.3% of patients who received antibody-rich plasma died compared to 29.6% of those given plasma with low level of antibodies Outcomes were better for those who were gi...
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