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CALQUENCE reduced the risk of disease progression or death by 71% vs. standard of care combinations at three years in the ASCEND Phase III trial

ELEVATE-RR head-to-head trial data also presented at ASH showed patients on ibrutinib experienced a 37% higher burden of adverse events of any grade while on treatment vs. patients on CALQUENCE ... | December 12, 2021
United States United Kingdom Liud Acalabrutinib Acerta Pharma National Cancer Institute American Society Of Clinical Oncology

New insights about COVID-19 vaccination rates among people living with HIV

The AIDS Clinical Trials Group, the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that insights around COVID-19 vaccination rates among people living with HV have been published in the Journal of Infectious Diseases.
United States South Africa Puerto Rico Harvard School Of Public Health Judith Currier Michael Lu

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'Significant differences' exist in COVID-19 vaccination rates among people with HIV

COVID-19 vaccination rates differ significantly among people with HIV, researchers found. According to a study published in the Journal of Infectious Diseases, factors that influence these differences include age, race, sex, body mass index and country of residence.
South Africa United States Steven Grinspoon Harvard Medical School Nutrition Obesity Research Center At Harvard Infectious Diseases
Source: healio.com

Frontiers | Chagas Disease Drug Discovery in Latin America—A Mini Review of Antiparasitic Agents Explored Between 2010 and 2021

Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that endangers almost 70 million people worldwide. The only two drugs that are currently approved for its treatment, benznidazole and nifurtimox, have controversial efficacy in adults and restricting safety issues, leaving thousands of patients without a suitable treatment. The neglect of Chagas disease is further illustrated by the lack of a robust and diverse drug discovery and development portfol...
United States El Salvador Pilar Manzano Fonseca Murta Oswaldo Cruz Van Huijsduijnen

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