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Frontiers | Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I

Cell entry of most alphaherpesviruses is mediated by the binding of glycoprotein D (gD) to different cell surface receptors. Equine herpesvirus type 1 (EHV-1) and EHV-4 gDs interact with equine major histocompatibility complex I (MHC-I) to initiate entry into equine cells. We have characterized the gD-MHC-I interaction by solving the crystal structures of EHV-1 and EHV-4 gDs (gD1, gD4), performing protein-protein docking simulations, surface plasmon resonance (SPR) analysis, and biological assay...
Mecklenburg Vorpommern United States New York Uppsala Lan United Kingdom Baden Wüberg

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Tenney backs bipartisan bills aimed at combating opioids

Press release: Congresswoman Claudia Tenney (NY-24), a member of the House Committee on Science, Space, and Technology, took part in a committee markup of seven bills, including H.R. 1734, the Testing, Rapid Analysis, and Narcotic Quality (TRANQ) Research Act. This bipartisan piece of legislation, which Rep. Tenney cosponsored, was led by Rep. Mike Collins (R-GA), Rep. Yadira
New York United States Yadira Caraveo National Institute Of Standards House Committee On Science Claudia Tenney

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