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Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

In a new study using a rat model of Crohn's disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn's disease.
United States Florinm Selaru Zhi Cheng Yao Sashank Reddy Jeffrey Chao Susan Gearhart

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Rehabilitation plus stem cell grafting after spinal cord injury can augment functional outcomes

In recent years, researchers have made measurable progress, using animal models, to promote tissue regeneration in spinal cord injuries (SCI) through implanted neural stem cells or grafts. Other efforts have shown that intensive physical rehabilitation can improve function after SCI by promoting greater or new roles for undamaged or spared cells and neural circuits.
San Diego United States University Of California San Diego Ashley Villarta Amandan Tran J Russell Huie

Potent antibiotic-loaded bone-cement could be used to treat bone infections

Each year, 700,000 people die due to antibiotic resistance. A growing global population unfortunately generates a growing resistance to established antibiotic treatments -; a threat that has been met with insufficient funding and dwindling inspiration, as commercial incentives for developing new antibiotics have fallen.
Lin Jang Shiladitya Sengupta Emily Henderson Department Of Orthopaedic Surgery Laboratory For Developing Advanced Biomaterials Brigham Center

Excessive smartphone use may lead to early puberty

Exposure to blue light via regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented today at the 60th Annual European Society for Paediatric Endocrinology Meeting.
Sprague Dawley Emily Henderson European Society For Paediatric Endocrinology Meeting Annual European Society Paediatric Endocrinology Aylin Kilin

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