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Novartis Pharma AG: Novartis Phase III APPOINT-PNH trial shows investigational oral monotherapy iptacopan improves hemoglobin to near-normal levels, leading to transfusion independence in all treatment-naïve PNH patients

Data at EBMT show primary endpoint met - estimated* 92.2% of complement-inhibitor-naïve patients with paroxysmal nocturnal hemoglobinuria (PNH) achieving 2 g/dL or more hemoglobin-level increase from baseline
South Korea France General United States Satoshi Sugimoto Julie Masow Giuseppe Moscati

Iptacopan Meets Primary End Point of APPOINT-PNH Trial in Paroxysmal Nocturnal Hemoglobinuria

Iptacopan elicited improved hemoglobin levels measuring at least 2 g/dL higher vs baseline, leading to transfusion independence after 24 weeks in approximately 92.2% of patients with complement inhibitorโ€“naรฏve paroxysmal nocturnal hemoglobinuria.
France General Antonio Risitano Giuseppe Moscati David Soergel Metabolism Development Unit Interest Group

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Caring for people is the most important aspect of the state policy of Turkmenistan

The events of the past week have become yet another vivid confirmation of the effectiveness of the constructive policy pursued by President Serdar Berdimuhamedov, aimed at the systematic and successful implementation of large-scale programs and project...
Ad Daw Ah United Arab Emirates Tajikistan General Republic Of Tajikistan Islamic Republic Of Iran Asia Viorel Gutu
Source: tdh.gov.tm

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