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The Atlantic Coronavirus Reinfection Will Soon Become Our Reality The virus can take many paths to reinvading a person’s body. Most of them shouldn’t scare us. On its face, reinfection appears to be a straightforward term. It is literally “infection, again” a recovered person’s second dalliance with the same microbe. Long written into the scientific literature of infectious disease, it is a familiar word, innocuous enough: a microbial echo, an immunological encore act. But thanks to the pandemic, reinfection has become a semantic and scientific mess. Newly saddled with the baggage of COVID-19, reinfection has taken on a more terrifying aspect, raising the specter of never-ending cycles of disease. It has sat at the center of debates over testing, immunity, and vaccines; its meaning muddled by ominous headlines, it has become wildly misunderstood. When I ask immunologists about reinfection in the context of the coronavirus, many sigh.

Katia koelleBrianne barkerAngela rasmussenGeorgetown universityEmory universityDrew universityContext of the coronavirusBodys immune strongholdsRoot of most coronavirus reinfectionsLast summerBodys abilityPeoples immune defensesImmune cellsImmune systemViruss movementsCluster of apparent cases reinfection