Page 16 - Research Article News Today

Science for just $15 USD. Resident help for fighting influenza Memory T cells take up residence in the lung after respiratory virus infection to facilitate rapid and localized immune responses during reinfection. Two studies in this week’s issue identify a population of CD4 + tissue–resident helper T cells in mice that are BCL6-dependent and support antiviral B cell responses within inducible bronchus-associated lymphoid tissue after influenza infection. Swarnalekha et al. used single-cell...

Necrotizing enterocolitis (NEC) is a devastating disease of premature infants characterized by acute intestinal necrosis and long-term neurological dysfunction, through mechanisms that are poorly understood. In new work, Zhou et al . study a neonatal mouse model of NEC, human brain autopsy specimens from infants with and without NEC, and human and mouse brain organoids. They report that CD4+ T lymphocytes, partially of intestinal origin, damage the developing brain of neonatal mice in the settin...

 E-Mail IMAGE: Researchers at the University of Tokyo have found a way to enhance the sensitivity of existing quantitative phase imaging so that all structures inside living cells can be seen simultaneously,... view more  Credit: s-graphics.co.jp, CC BY-NC-ND Experts in optical physics have developed a new way to see inside living cells in greater detail using existing microscopy technology and without needing to add stains or fluorescent dyes. Since individual cells are almost transl...

 E-Mail IMAGE: Representative specimen image of Anopheles stephensi from Mosquito Image Database. Picture shows a mosquito stored by freezing at -80C. view more  Credit: Couret, J. et al. 2020 (CC-BY 2.0) Rapid and accurate identification of mosquitoes that transmit human pathogens such as malaria is an essential part of mosquito-borne disease surveillance. Now, researchers reporting in PLOS Neglected Tropical Diseases have shown the effectiveness of an artificial intelligence system...

Science for just $15 USD. Excoriating exosomes Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe, potentially deadly drug-induced cutaneous reactions that result in skin death and detachment. Zhang et al. show that plasma exosomes from patients with SJS/TEN entered and promoted the apoptosis of primary human keratinocytes. They found that miR-375-3p was abundant in the patient-derived exosomes and correlated with clinical severity, and further showed that this mic...

 E-Mail IMAGE: Researchers aboard the research vessel Mirai watched water vapor rise from the Chukchi Sea, resembling the mist that rises from a hot bath in a cold room. The Pacific Ocean... view more  Credit: Photo by Jun Inoue, National Institute of Polar Research, CC BY-SA. Experts in Japan recently discovered that atmospheric conditions near Alaska can affect sea ice conditions in the Arctic Ocean months later. The team used various data, including ship-based data from 2018, to un...