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Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies | BMC Medicine

Up to one of every six individuals diagnosed with one cancer will be diagnosed with a second primary cancer in their lifetime. Genetic factors contributing to the development of multiple primary cancers, beyond known cancer syndromes, have been underexplored. To characterize genetic susceptibility to multiple cancers, we conducted a pan-cancer, whole-exome sequencing study of individuals drawn from two large multi-ancestry populations (6429 cases, 165,853 controls). We created two groupings of i...
Kaiser Permanente Research Bank Research Program On Genes Regeneron Genetics Center United Kingdom Biobank Research Program East Asian

URI STEEP science effort responding to 'forever' PFAS chemical pollution renewed for $8.1 million for another 5 years – URI News

Against the backdrop of a new federal undertaking to address PFAS pollution, a University of Rhode Island-based PFAS research-and-outreach program has been renewed by the government for another five years. The STEEP (Sources, Transport, Exposure and Effects of Per- and polyfluorinated alkyl Contaminants) program, one of the longer running PFAS science efforts in the country, studies pollution and examines potential research-based solutions alongside community partners. ...
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Source: uri.edu

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