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Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.
United States University Of North Carolina Drug Administration Clinical Brexanolone Program United States Food Risk Evaluation

Kite's Car T-cell Therapy Yescarta® Demonstrates High Response Rate and Durable Remission in ALYCANTE Study as Initial Treatment for Transplant Ineligible Patients With Relapsed/Refractory Large B-cell Lymphoma

โ€“ Yescarta Achieved a Complete Metabolic Response of 71% at 3 Months Versus 12% Expected with Historical Standard of Care Controls โ€“ โ€“ Results Published in Nature Medicineโ€“ ...
United States Santa Monica Foster City Frank Neumann Roch Houot Gilead Sciences Inc

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GNW-Adhoc: Idorsia reacquires the world-wide rights to aprocitentan

^Ad hoc announcement pursuant to Art. 53 LR * Aprocitentan, Idorsia's oral, dual endothelin receptor antagonist is currently under review with health authorities for the treatment of patients with resistant hypertension. * Idorsia will pay Janssen a conditional consideration up to a total cap of...
Switzerland General United States Jean Paul Clozel Markus Schlaich Janssen Biotech Inc Janssen Pharmaceutical Companies

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