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Engineered safety switch curbs severe side effects of CAR-T immunotherapy

 E-Mail IMAGE: Matthew Foster, MD, and his UNC Lineberger colleagues have used an experimental safety switch incorporated as part of a chimeric antigen receptor-modified T cell therapy (CAR-T) for an aggressive form. view more  Credit: UNC Lineberger Comprehensive Cancer Center CHAPEL HILL, North Carolina UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur. This advance was seen in a patient enrolled in a clinical trial using CAR-T to treat refractory acute B-cell leukemia. It demonstrates a proof-of-principle for possible expanded use of CAR-T immunotherapy paired with the safety switch.

General Assembly elects new judges, including successor to Roanoke judge who quietly left midterm

RICHMOND — The General Assembly elected new judges Tuesday to benches around the Roanoke Valley, including someone to fill a vacancy left by a Roanoke Juvenile and Domestic Relations District judge who recently and quietly stepped down. Heather Ferguson will succeed John Weber III, who became a domestic court judge in 2015. His first term on the bench was due to extend through June, and his motivation for departing early has not been announced and remains unclear. Judge Hilary Griffith, chief of Juvenile and Domestic Relations District Court in the 23rd Judicial District, confirmed last week that Weber had left, but referred questions about his departure to the Virginia Supreme Court’s executive secretary. That office did not immediately respond to messages left this week.

Морковка для русских или Безвиз для россиян Сработает ли?

Морковка для русских или Безвиз для россиян Сработает ли?
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Хороших отношений между Россией и США не будет никогда

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И снова печеньки! Виктория Нуланд возвращается в Госдеп США

И снова печеньки! Виктория Нуланд возвращается в Госдеп США
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