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Brain Wave Recordings Reveal Potential for Individualized Parkinson s Treatments

Date Time Brain Wave Recordings Reveal Potential for Individualized Parkinson’s Treatments Pioneering neural recordings in patients with Parkinson’s disease by UC San Francisco scientists are providing the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders. In a study published May 3 in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson’s. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson’s symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient brain waves.

Pioneering neural recordings lay the groundwork for personalized Parkinson s treatments

Pioneering neural recordings lay the groundwork for personalized Parkinson s treatments Pioneering neural recordings in patients with Parkinson s disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson s and other neurological disorders. In a study published May 3rd in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson s. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson s symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient brain waves.

Parkinson s disease brain activity recorded with pocket-sized wireless device

Parkinson s disease brain activity recorded with pocket-sized wireless device
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Brain wave recordings reveal potential for individualized Parkinson s treatments

 E-Mail Pioneering neural recordings in patients with Parkinson s disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson s and other neurological disorders. In a study published May 3rd in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many months, with and without deep brain stimulation (DBS) therapy. Pairing the brain recordings with wearable monitors of movement, they identified patterns of brain activity corresponding to specific movement abnormalities associated with Parkinson s. Their research provides the first evidence, during normal activities of daily living, for a long-held hypothesis that Parkinson s symptoms are related to erratic brain wave patterns, and demonstrate how DBS restores order to patient brain waves.

Researchers wirelessly record human brain activity during normal life activities

 E-Mail IMAGE: Implanted electrodes stream recorded data to a pocket-sized device worn by a patient. The data are then wirelessly transferred to a tablet and then uploaded to the cloud via a. view more  Credit: Image courtesy of Starr lab, UCSF Researchers are now able to wirelessly record the directly measured brain activity of patients living with Parkinson s disease and to then use that information to adjust the stimulation delivered by an implanted device. Direct recording of deep and surface brain activity offers a unique look into the underlying causes of many brain disorders; however, technological challenges up to this point have limited direct human brain recordings to relatively short periods of time in controlled clinical settings.

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