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Association of pneumococcal carriage in infants with the risk of carriage among their contacts in Nha Trang, Vietnam: A nested cross-sectional survey

Author summary Why was this study done? There is little information in the current literature on pneumococcal transmission to infants. Since individuals in this age group are at major risk of pneumococcal disease and at potentially reduced protection in reduced dose pneumococcal vaccination schedules, we carried out a study to identify their close contacts and likely routes of transmission. What did the researchers do and find? We identified all 7,428 physical contacts of 1,583 infants in Nha Trang, a coastal city in Vietnam. We found that there was a high correlation between infant infection and their probability of contact with at least 1 pneumococcal carrier on the surveyed day. Preschool-age children contributed around half of the total direct pneumococcal exposure risk to infants in Nha Trang. Around 80% of the exposure risk came from contact with household members. What do these findings mean? Social contact surveys can help to identify possible transmission pathways. I

Social connections influence brain structure of rhesus macaques

How immunity from and interaction with seasonal coronaviruses can shape SARS-CoV-2 epidemiology

Cross-protection from seasonal epidemics of human coronaviruses (HCoVs) has been hypothesized to contribute to the relative sparing of children during the early phase of the pandemic. Testing this relies on understanding the prepandemic age distribution of recent HCoV infections, but little is known about their dynamics. Using England and Wales as a case study, we use a transmission model to estimate the duration of immunity to seasonal coronaviruses, and show how cross-protection could have affected the age distribution of susceptibility during the first wave, and could alter SARS-CoV-2 transmission patterns over the coming decade.

NI primary school children describe their joy at being back with their friends

NI primary school children describe their joy at being back with their friends
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