Page 30 - Rush Memory News Today

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study Vijay R. Varma , Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing ¶‡ These authors share first authorship on this work. Affiliation Clinical and Translational Neuroscience Section, Laboratory ...

11 Dec 2020 It is difficult to isolate large quantities of microglia from human brain. That’s why scientists still know little about the different ways these cells rear up in health and disease. A new single-cell—not single-nucleus—RNA-sequencing study led by Philip De Jager at Columbia University, New York, sheds some light on this. It analyzed the largest number of microglia yet, totaling more than 16,000, isolated from the brains of people with Alzheimer’s disease and normal cognitio...