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Study depicts previously unknown molecular mechanism underlying healthy brain development
A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.
The study, published in the Journal of Neuroscience, depicts a previously unknown molecular mechanism underlying healthy brain development. This insight could one day help scientists establish the basis for developing new drugs that mature or repair cellular networks and mitigate disease.
Neurons and glia are the most abundant types of brain cells. Glia, in particular star-shaped glia called astrocytes, release signaling molecules that support the growth and maintenance of healthy synapses, the chemical communication structures between neurons.