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Confined magnetic colloidal system for controllable fluid transport

 E-Mail Credit: ©Science China Press Colloidal suspensions of microscopic particles show complex and interesting collective behaviors. In particular, the collective dynamics of colloids is fundamental and ubiquitous for materials assembly, robotic motion, microfluidic control, and in several biological scenarios. The collective dynamics of confined colloids can be completely different from that of free colloids: for instance, confined colloids can self-organize into vortex structures, coheren...
Jing Liu Jianyu Li Xu Hou Xinyu Chen Zhizhi Sheng Rongrong Zhang

Role of cell cycle on analyzing telomerase activity with a fluorescence off-on system

 E-Mail IMAGE: AIEgen-based fluorescence detecting system for analysis of TERT mRNA and telomerase activity in different phases of cell cycle (G0/G1, G1/S, S and G2/M phase). view more  Credit: @Science China Press Cancer is a significant cause of death worldwide and many efforts have been devoted to the development of methods for early detection. Telomerase are considered as a tumor biomarker for early diagnosis because the telomerase of more than 80% immortalized cells are reactivat...
Ifeng Wu Xiaoding Lou Xia Wu Biao Chen Jun Wu Jun Dai

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Bioorthogonally catalyzed lethality strategy generates targeting drugs within tumor

Credit: @Science China Press Cancer is the second leading cause of death in the world. The number of deaths and incidences is increasing each year. The metal-based anticancer drugs were used clinically worldwide, but suffer from poor selectivity, serious side effects and drug resistance. Tumor-targeting drug development is the basis for precise cancer treatment. Recently, Professor Hongke Liu of Nanjing Normal University, Professor Jing Zhao and Academician Zijian Guo of Nanjing University hav...
Jing Zhao Yong Qian Qin Tao Hongke Liu Chenggen Qian Zijian Guo

Confined growth of ZIF-8 in organosilica nanoparticles to regulate mRNA translation

 E-Mail IMAGE: (a) cellular uptake, (b) endosomal escape, (c) GSH depletion contributed by tetrasulfide-induced GSH oxidation and zinc-mediated inhibition of GR and GSSG reduction, (d) GAPDH deactivation, (e) increased MMP, (f) mTORC1... view more  Credit: @Science China Press Delivery of genetic molecules such as mRNA into cells is vital with important applications such as vaccine development. Various agents have been developed for mRNA delivery. However, conventional mRNA nanocarrie...
Liye Zhang Chao Liu Yue Wang Jie Tang Yannan Yang Chengzhong Yu

2D CaCl crystals with +1 calcium ions displaying unexpected metallicity and ferromagnetism

 E-Mail IMAGE: (a) Schematic drawings of the sample preparation processes. (b) (i) Cryo-EM image of the Ca-Cl crystals in the ultra-thin reduced graphene oxide (rGO) membrane. (ii) Diffraction pattern of a typical... view more  Credit: @Science China Press Calcium ions are presented in rocks, bones, shells, biominerals, geological deposits, ocean sediments, and many other important materials. Calcium ions also play major roles in the retention of carbon dioxide in natural waters, wate...
Liang Chen Xing Liu Lu Gou Xpeng Zhang Yimin Zhao Jie Jiang

Reversible superoxide-peroxide conversion drives high-capacity potassium-metal batte

 E-Mail IMAGE: (a) Theoretical output potential, specific capacity and energy density for the KO2 and other typical K-ion battery cathodes. (b) XRD pattern and TEM images of KO2-RuO2@rGO cathode composites. The XRD... view more  Credit: @Science China Press There is an urgent need for high-energy-density rechargeable batteries to further satisfy the ever-growing demand for electrical energy storage devices. Triggering the O-related anionic redox activities (e.g. typical Li/Na/K-O2 bat...
Zhi Chang Chan Deng Xin Cao Haoshen Zhou Huijun Yang National Basic Research Program Of China

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